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Hitman: Absolution is an upcoming third person shooter being developed by IO Interactive and published by Square Enix. It is the upcoming fifth entry in the Hitman game series, and will run on IO Interactive's proprietary Glacier 2 game engine. The developers have confrimed that Absolution will feature different gameplay than previous installments, with a greater focus on action and gunplay.

Hitman: Blood Money ended with Diana helping Agent 47 fake his death, in order for him to escape The Franchise. 47 killed their leader, former FBI director Alexander Leland Cayne, though he was part of a larger secret society called Alpha Zerox. Diana and the rest of ICA do not know 47's whereabouts, nor does the player for certain - though the last scene shows 47 entering an Asian establishment, asking suspiciously what they have to offer, "preferably in the back". The first in-depth trailer for the game shows Agent 47 storming a safehouse, and confronting Diana while she is showering. 47 is "betrayed by those he once trusted and now hunted by the police, he suddenly finds himself at the center of a dark conspiracy and must embark on a personal journey through a corrupt and twisted world, in his search for the truth". At least one portion of the game will be set in Chicago, but it has been confirmed that the rest of the game will take place within the US. Hitman: Absolution is not set in a specific Hitman timeline. Confirmed plot details include series protagonist Agent 47 assassinating his former International Contract Agency handler Diana Burnwood early in the game and the antagonist identified as Blake Dexter, a new character to the series. The character will be voiced by Keith Carradine. There will be a significant amount of blood and gore in Hitman: Absolution.
Release date: November 20, 2012.

Source: http://hitman.com